Tranmere's three game unbeaten run came to an end as a goal either side of half time gave Carlisle a 2-0 win at Brunton Park.
Rovers had the chance to take the lead midway through the first half when they were awarded a penalty, but Ian Thomas-Moore's perfect record from the spot for the Club came to an end when his effort was saved.
Peter Gulacsi produced a penalty save of his own on 37 minutes but the home side went ahead just a few minutes later and doubled their lead five minuets into the second half.&nbsp;&nbsp;
Les Parry made just one change to the side that started in the 4-2 win over MK Dons, with Aaron Cresswell returning from injury to take the place of the suspended Zoumana Bakayogo at left back. Former Rovers striker Craig Curran was named among the Carlisle substitutes.
Despite the heavy rain that had fallen on Brunton Park for several hours before kick off the playing surface looked in excellent condition for kick off.
Peter Gulacsi made a comfortable save from Francois Zoko at his near post on five minutes while Marlon Broomes' slide tackle prevented the midfielder from a one on one with the Rovers keeper a couple of minutes later.
Enoch Showunmi headed narrowly wide from a deep Cresswell free kick on eight minutes for Tranmere's first effort of the game while Gulacsi held on to Ben Marshall's free kick two minutes later at the other end.
James Berrett fired high over the Tranmere bar from 25 yards on 12 minutes and the Gulacsi pulled off a fine reaction save to palm Peter Murphy's close range header over the bar soon after as the hosts won a succession of corners.
Zoko put a powerful right foot effort just over the bar on 20 minutes but three minutes later the action moved to the other end and Rovers were awarded a penalty. Dale Jennings skipped past Frank Simek to latch on to a high ball from Goodison, ran into the area and after his initial shot was blocked, the ball fell to Welsh who was brought down by Murphy with the referee pointing straight to the spot. However, Ian Thomas-Moore saw his low effort well saved by Adam Collin and the game remained all square.
A poor clearance fell to Jennings 40 yards out on 29 minutes and the striker's pace took him straight past one challenge before he laid the ball off to Labadie. The midfielder cut inside one attempted tackle before seeing his attempted curler deflect away for a corner.
Carlisle's on loan centre back Lubomir Michalik sent a 40 yard free kick well wide of the target on 31 minutes and Welsh headed wide from a Thomas-Moore cross soon after.
It was a penalty apiece on 36 minutes when Cresswell's attempted clearance failed and Goodison was adjudged to have brought down Zoko, but the score remained goalless as Gulacsi dived to his right to save Gary Madine's spot kick, the second penalty the Carlisle man had had saved in under 40 minutes of football.
However, six minutes later the home side took the lead, with Zoko holding the ball up in the area before Berrett unleashed an unstoppable shot into the left side of the net to put Carlisle ahead at half time.
Thomas-Moore headed wide from a Cresswell corner in the first minute of the second half, but the next attack put Carlisle two goals up. A corner from the right was swung in by Berrett and Murphy headed in from close range.
Rovers' first change saw Lucas Akins replace Cathalina on 56 minutes with Blanchard moving to right back and the formation changing to 4-4-2, Jennings and Thomas-Moore moving out wide.
Akins shot harmlessly wide on 64 minutes and a Jennings effort was sliced past the target three minutes later, with Broomes seeing his low effort saved from the corner that was bizarrely awarded.
On 71 minutes Jennings ran on to Showunmi's flick on and played the ball back to the big striker, but his effort from the penalty spot went high over the Carlisle goal.
Thomas-Moore and Cresswell both failed with speculative efforts as Rovers looked for a way back into the game and a Goodison close range header was blocked for a corner.
A long range shot from Labadie was parried by Collin on 85 minutes with Showunmi ruled offside as he attempted to pounce on the rebound. The Carlisle keeper was quickly off his line moments later to clear before Showunmi and Akins could reach the ball, while Curran fired wide at the other end.
Carlisle: Collin, Simek, Murphy, Robson, Taiwo, Zoko (Curran 78), Marshall, Madine, Berrett, Michalik, Grella. Substitutes not used: Hurst, Kane, Cook, Caig, McKenna, Evans.
Tranmere: Gulacsi, Cathalina (Akins 56), Broomes, Goodison, Cresswell, Labadie, Blanchard, Welsh, Thomas-Moore, Showunmi, Jennings. Substitutes not used: Collister, Darville, Grandison, Fraughan, McGurk, Morrow.
Referee: Eddie Ilderton
Yellow cards: Murphy (24), Goodison (37), Marshall (40), Cathalina (44)
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