It’s the second of back-to-back away trips for Rovers as they look to continue the unbeaten run with a trip to Essex to face Colchester United.
Rovers are unbeaten in their last three games after two vital home wins were followed by a share of the spoils away at Gander Green Lane last time out as Sutton United held Micky Mellon’s side to a point.
After a dominant second-half display, Micky will be hoping that his side can replicate the second 45 minutes from Saturday and begin the game in the same fashion as they left off in south London.
As for Colchester, they had to wait until Monday to play their game as they appeared on Sky Sports coverage for their clash with league leaders Forest Green Rovers.
Unfortunately for United, an early goal from Matt Stevens in the 9th minute was the difference as Forest Green ran out 1-0 winners.
With Colchester having won just two of their last ten games, they will be hoping to improve their form between now and the end of the season, starting with facing Tranmere on Saturday afternoon.
Jay Spearing will return to the squad after being out for a period with an injury. Kieron Morris will continue to be assesses following his shoulder injury.
Lee O'Connor is away on international duty with Republic of Ireland U21s.
One to watch: Freddie Sears
A player who has always been renowned for scoring goals across the EFL, Freddie Sears has done well for Colchester this year in what has been a tough year for the U’s.
Having broken through at West Ham, Sears experienced a number of loan spells including a year at Colchester which led to a permanent move the season after.
In 2015, Sears left United to join Ipswich Town, a spell in which lasted six seasons and saw him make over 200 appearances for the Tractor Boys before moving back to Colchester.
With over 15 goal contributions this season, Sears will be looking to add to his tally on Saturday as he looks to claim Colchester’s top scorer award this season.
Manager: Wayne Brown
After being named interim manager for Colchester in January, Wayne Brown is no stranger to the interim role having been on the touchline in two different spells for the U’s after spending time there as a player.
He made over 100 appearances for United, including playing a role in their promotion winning side in 2005/06 which saw the Essex side promoted to the Championship.
Brown featured for a number of clubs during his playing career including spells at Ipswich Town , Watford, Preston North End and Leicester City.
Since taking the reigns in January, Brown has seen his side win four games and will be hoping to see a few more victories to ensure Colchester steer well clear of the relegation places as the season draws to a thrilling finale.
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You can follow the action through our social media channels below, with full text coverage during the fixture, followed by a match report.
Match reaction from Micky Mellon and a player will follow on our website and YouTube channel.